The first 9-hydroxyhomoisoflavanone, and antiplasmodial chalcones, from the aerial exudates of Polygonum senegalense

  title={The first 9-hydroxyhomoisoflavanone, and antiplasmodial chalcones, from the aerial exudates of Polygonum senegalense},
  author={J. Midiwo and Fidilia M. Omoto and A. Yenesew and H. Akala and Julia M. Wangui and P. Liyala and C. Wasunna and N. Waters},
Phytochemical re-examination of the aerial exudates of Polygonum senegalense forma senegalense has resulted in the isolation and characterization of a novel homoisoflavonoid, 5,7- dihydroxy-3-(hydroxy-phenyl-methyl)-6-methoxy-chroman-4-one (trivial name: polygohomoisoflavanone). The structure was determined on the basis of spectroscopic evidence. The new compound along with other components of the aerial exudate showed good antiplasmodial activities towards chloroquine-sensitive (D6) and… Expand

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