The fimbrin and alpha-actinin footprint on actin

  title={The fimbrin and alpha-actinin footprint on actin},
  author={Paul Matsudaira},
  journal={The Journal of Cell Biology},
  pages={285 - 287}
satisfying experience in science occurs when information from several areas converge to give a big picture about an important problem. In three papers (Holtz-man et al. in this issue of The Journal of Cell Biology, the disciplines of genetics and structural biology have revealed that two ac-tin cross-linking proteins, fimbrin and alpha-actinin, bind to the same region on actin. Because both proteins belong to a superfamily of actin cross-linking proteins, we have some confidence that other… CONTINUE READING