The filamentous phages fd and IF1 use different mechanisms to infect Escherichia coli.

@article{Lorenz2011TheFP,
  title={The filamentous phages fd and IF1 use different mechanisms to infect Escherichia coli.},
  author={Stefan H. Lorenz and Roman P Jakob and Ulrich Weininger and Jochen Balbach and Holger Dobbek and Franz Xaver Schmid},
  journal={Journal of molecular biology},
  year={2011},
  volume={405 4},
  pages={989-1003}
}
The filamentous phage fd uses its gene 3 protein (G3P) to target Escherichia coli cells in a two-step process. First, the N2 domain of G3P attaches to an F pilus, and then the N1 domain binds to TolA-C. N1 and N2 are tightly associated, rendering the phage robust but noninfectious because the binding site for TolA-C is buried at the domain interface. Binding of N2 to the F pilus initiates partial unfolding, domain disassembly, and prolyl cis-to-trans isomerization in the hinge between N1 and N2… CONTINUE READING

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