The filamentous haemagglutinin, a multifaceted adhesion produced by virulent Bordetella spp.

@article{Locht1993TheFH,
  title={The filamentous haemagglutinin, a multifaceted adhesion produced by virulent Bordetella spp.},
  author={Camille Locht and Philippe N. Bertin and Franco Menozzi and German F S{\'a}enz Renauld},
  journal={Molecular microbiology},
  year={1993},
  volume={9 4},
  pages={
          653-60
        }
}
Filamentous haemagglutinin (FHA) is the major attachment factor produced by virulent Bordetella spp. Similar to the other virulence factors, its production is tightly regulated by a two-component system in response to environmental changes. Although of impressive size (c. 220 kDa), it is very efficiently released into the culture supernatant of Bordetella pertussis. Its biogenesis involves complex processing of a larger precursor with a calculated molecular mass of 370 kDa. Export of FHA into… CONTINUE READING
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