The fibrinogen binding protein of Staphylococcus epidermidis is a target for opsonic antibodies.

@article{Rennermalm2004TheFB,
  title={The fibrinogen binding protein of Staphylococcus epidermidis is a target for opsonic antibodies.},
  author={Anna Rennermalm and Madeleine Nilsson and Jan-Ingmar Flock},
  journal={Infection and immunity},
  year={2004},
  volume={72 5},
  pages={3081-3}
}
Antibodies against the fibrinogen binding protein (Fbe) of Staphylococcus epidermidis significantly increased macrophage phagocytosis. Antibodies against autolysin E were opsonic but to a lesser extent. Antibodies against a novel, putatively surface-located antigen were unable to enhance phagocytosis. The severity of systemic infection of mice with S. epidermidis was reduced if the bacteria were preopsonized with anti-Fbe prior to administration. Fbe is thus a strong candidate for protein… CONTINUE READING