The fetal environment: a critical phase that determines future renal outcomes in autosomal dominant polycystic kidney disease.

Abstract

Orskov and colleagues demonstrate the impact of birth weight on the mean age of end-stage renal disease (ESRD) in a large Danish ADPKD cohort. Each kilogram of birth weight extended the mean age of ESRD onset by 1.7 years. Placental insufficiency, activation of the renin-angiotensin-aldosterone system, increased fetal vasopressin levels, compensatory… (More)
DOI: 10.1038/ki.2012.8

Topics

Cite this paper

@article{Chapman2012TheFE, title={The fetal environment: a critical phase that determines future renal outcomes in autosomal dominant polycystic kidney disease.}, author={Arlene B. Chapman}, journal={Kidney international}, year={2012}, volume={81 9}, pages={814-5} }