The ferroportin metal efflux proteins function in iron and cobalt homeostasis in Arabidopsis.

@article{Morrissey2009TheFM,
  title={The ferroportin metal efflux proteins function in iron and cobalt homeostasis in Arabidopsis.},
  author={Joe Morrissey and Ivan Baxter and Joohyun Lee and Liangtao Li and Brett Lahner and Natasha Grotz and Jerry Kaplan and David E. Salt and Mary Lou Guerinot},
  journal={The Plant cell},
  year={2009},
  volume={21 10},
  pages={3326-38}
}
Relatively little is known about how metals such as iron are effluxed from cells, a necessary step for transport from the root to the shoot. Ferroportin (FPN) is the sole iron efflux transporter identified to date in animals, and there are two closely related orthologs in Arabidopsis thaliana, IRON REGULATED1 (IREG1/FPN1) and IREG2/FPN2. FPN1 localizes to the plasma membrane and is expressed in the stele, suggesting a role in vascular loading; FPN2 localizes to the vacuole and is expressed in… CONTINUE READING
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