The feasibility of intracarotid adenosine for the manipulation of human cerebrovascular resistance.

@article{Joshi1998TheFO,
  title={The feasibility of intracarotid adenosine for the manipulation of human cerebrovascular resistance.},
  author={Shailendra Joshi and William L. Young and John Pile-Spellman and D. Hoang Duong and Meng C Vang and Lotfi Hacein-Bey and Heewon Lee and Noeleen D. Ostapkovich},
  journal={Anesthesia and analgesia},
  year={1998},
  volume={87 6},
  pages={1291-8}
}
UNLABELLED To assess the feasibility of manipulating human cerebrovascular resistance with adenosine, we measured cerebral blood flow (CBF) by determining the initial slope (IS) of tracer washout 20-80 s after intracarotid 133Xe injection (standard IS) during sequential 3-min intracarotid infusions of (a) saline; (b) adenosine 1.2-mg bolus followed by an… CONTINUE READING