The fatty acid composition of sphingomyelin from adult human cerebral white matter and changes in childhood, senium and unspecific brain damage

@article{Heipertz1977TheFA,
  title={The fatty acid composition of sphingomyelin from adult human cerebral white matter and changes in childhood, senium and unspecific brain damage},
  author={R. Heipertz and Hartmut Pilz and Winfried Scholz},
  journal={Journal of Neurology},
  year={1977},
  volume={216},
  pages={57-65}
}
A micromethod for the investigation of the fatty acid composition of sphingomyelin is presented. In the cerebral white matter of 17 normal adult brains, analyzed for reference, the predominant fatty acids are C 18:0 and C 24:1. Our results are in agreement with those of other authors. Short chained fatty acids are relatively increased in young children; this shift is typical of “immature” myelin. Similar changes are described here in old persons and cases of non-specific brain damage associated… CONTINUE READING
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