The fate of severed corticospinal axons.

  title={The fate of severed corticospinal axons.},
  author={Paul S. Fishman and J. Patrick Kelley},
  volume={34 9},
The potential for regeneration of severed corticospinal axons was examined by labeling these axons with horseradish peroxidase following thoracic spinal cord transections in mice. Shortly after severance, the proximal ends of corticospinal axons formed terminal bulbs that persisted for weeks and were associated with axonal retraction. There were few signs of corticospinal axonal sprouting or elongation. By 2 months after injury, corticospinal axons near the transection site showed an increased… CONTINUE READING