The fate of competing beneficial mutations in an asexual population

@article{Gerrish2004TheFO,
  title={The fate of competing beneficial mutations in an asexual population},
  author={P. Gerrish and R. Lenski},
  journal={Genetica},
  year={2004},
  volume={102-103},
  pages={127-144}
}
  • P. Gerrish, R. Lenski
  • Published 2004
  • Medicine, Biology
  • Genetica
  • In sexual populations, beneficial mutations that occur in different lineages may be recombined into a single lineage. In asexual populations, however, clones that carry such alternative beneficial mutations compete with one another and, thereby, interfere with the expected progression of a given mutation to fixation. From theoretical exploration of such ‘clonal interference’, we have derived (1) a fixation probability for beneficial mutations, (2) an expected substitution rate, (3) an expected… CONTINUE READING

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