The family of human Na,K-ATPase genes. ATP1AL1 gene is transcriptionally competent and probably encodes the related ion transport ATPase.

@article{Modyanov1991TheFO,
  title={The family of human Na,K-ATPase genes. ATP1AL1 gene is transcriptionally competent and probably encodes the related ion transport ATPase.},
  author={Nikolai N. Modyanov and Konstantin Petrukhin and Vladimir E. Sverdlov and Alexander V Grishin and M Y Orlova and Maria B Kostina and O I Makarevich and Natalia E. Broude and G. S. Monastyrskaya and E. D. Sverdlov},
  journal={FEBS letters},
  year={1991},
  volume={278 1},
  pages={91-4}
}
The multigene family of human Na,K-ATPase is composed of 5 alpha-subunit genes, 3 of which were shown to encode the functionally active alpha 1, alpha 2 and alpha 3 isoforms of the catalytic subunits. This report describes the isolation, mapping and partial sequencing of the fourth gene (ATP1AL1) that was demonstrated here to be functionally active and expressed in human brain and kidney. Limited DNA sequencing of the ATP1AL1 exons allowed one to suggest that the gene probably encodes a new ion… CONTINUE READING

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