The factors affecting plasma glutathione peroxidase and selenium in rheumatoid arthritis: a multiple linear regression analysis.

@article{Honkanen1991TheFA,
  title={The factors affecting plasma glutathione peroxidase and selenium in rheumatoid arthritis: a multiple linear regression analysis.},
  author={V. E. A. Honkanen},
  journal={Scandinavian journal of rheumatology},
  year={1991},
  volume={20 6},
  pages={385-91}
}
The reactive oxygen radicals are trapped by anti-oxidants, such as selenium containing glutathione peroxidase (GSHpx), which also can inhibit the oxygenation of arachidonic acid to pro-inflammatory prostaglandins and leukotrienes. We studied the levels of anti-oxidant glutathione peroxidase and selenium (in plasma) in 48 patients with rheumatoid arthritis (RA). In the multiple regression model, joint score had the highest explanatory value for serum selenium, and sulphasalazine treatment was… CONTINUE READING