The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan.

Abstract

Recent studies in Caucasian populations have shown an association of the Leiden mutation in factor V with preeclampsia (PE). It consists of a substitution of a G (G1691) with an A (A1691) at nucleotide position 1691 in exon 10, resulting in arginine instead of glutamine at residue 506 at the factor V cleavage site for activated protein C (APC); it… (More)

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Cite this paper

@article{Kobashi1999TheFV, title={The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan.}, author={G. Kobashi and Hiroyuki Yamada and Tomoichiro Asano and Seiji Nagano and Akira Hata and Reiko Kishi and Kazunao Kondo and Shimpei Fujimoto}, journal={Seminars in thrombosis and hemostasis}, year={1999}, volume={25 5}, pages={487-9} }