The facial motor nucleus transcriptional program in response to peripheral nerve injury identifies Hn1 as a regeneration‐associated gene

@article{Zujovic2005TheFM,
  title={The facial motor nucleus transcriptional program in response to peripheral nerve injury identifies Hn1 as a regeneration‐associated gene},
  author={Violetta Zujovic and Defang Luo and Henry V Baker and M. Cecilia L{\'o}pez and Kelly R. Miller and Wolfgang J Streit and Jeffrey K. Harrison},
  journal={Journal of Neuroscience Research},
  year={2005},
  volume={82}
}
Facial nerve axotomy (FNA) is a well‐established experimental model of motoneuron regeneration. After peripheral nerve axotomy, a sequence of events including glial activation and axonal regrowth leads to functional recovery of the afflicted pool of motoneurons. Using microarray analysis we identified an increase in the expression of 60 genes (at a false discovery rate of 0.1, genes were significant P < 0.004) within the facial nucleus as a consequence of nerve injury. In situ hybridization… Expand
Differential gene expression in the axotomized facial motor nucleus of presymptomatic SOD1 mice
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gp130 cytokines are positive signals triggering changes in gene expression and axon outgrowth in peripheral neurons following injury
  • R. Zigmond
  • Biology, Medicine
  • Front. Mol. Neurosci.
  • 2012
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