The eye photoreceptor protein rhodopsin. Structural implications for retinal disease 1

  title={The eye photoreceptor protein rhodopsin. Structural implications for retinal disease 
  author={P. Garriga and J. Manyosa},
  journal={FEBS Letters},
  • P. Garriga, J. Manyosa
  • Published 2002
  • Biology, Medicine
  • FEBS Letters
  • Rhodopsin is the membrane receptor responsible for photoreception in the vertebrate retina. Its characteristic seven‐transmembrane helical structural motif is today widely recognised as a paradigm in signal transduction. Rhodopsin and the phototransduction system are frequently used as structural and mechanistic models for the G‐protein coupled receptor superfamily. Recent advances in the activation mechanism (as derived from the structural available data) and the implications for normal and… CONTINUE READING
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