The eye in hypertension

@article{Wong2007TheEI,
  title={The eye in hypertension},
  author={Tien Yin Wong and Paul Mitchell},
  journal={The Lancet},
  year={2007},
  volume={369},
  pages={425-435}
}

Figures from this paper

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References

SHOWING 1-10 OF 191 REFERENCES

Regression of retinal vascular changes by antihypertensive therapy.

Even long-standing nonmalignant hypertension seems not to damage retinal tissue, and this may be explained by a regain of autoregulation which allows the arteriolonecrotic lesions to heal.

Retinopathy in older persons without diabetes and its relationship to hypertension.

This study supports the Beaver Dam Eye Study findings that retinal hemorrhages and microaneurysms are relatively frequent lesions in older people without diabetes and are significantly related to the presence and severity of hypertension.

Is blood pressure a predictor of the incidence or progression of diabetic retinopathy?

After controlling for other risk variables, systolic blood pressure remained a significant predictor of the incidence of diabetic retinopathy; diastolicBlood pressure was of borderline significance in predicting progression in the younger-onset group.

Retinal microvascular abnormalities and renal dysfunction: the atherosclerosis risk in communities study.

Retinal microvascular abnormalities are associated with renal dysfunction, suggesting that common systemic microv vascular processes may underlie the development of microVascular damage in the eye and kidneys.

Hypertensive retinopathy and incident coronary heart disease in high risk men

The data support the concept that retinal microvascular changes are markers of blood pressure damage and may be useful in risk stratification and in the tailoring of hypertension treatment decisions.

The effect of experimental hypertension on retinal vascular autoregulation in humans: a mechanism for the progression of diabetic retinopathy

An impairment in retinal vascular autoregulation in response to raised systemic blood pressure in diabetic subjects, more so at an elevated blood glucose level is demonstrated, thus providing a mechanism for the detrimental effect of hypertension on diabetic retinopathy.

Retinal arteriolar diameters and elevated blood pressure: the Atherosclerosis Risk in Communities Study.

The patterns of association suggested that these signs reflect both transient and persisting structural effects of elevated blood pressure, in agreement with the scant pathologic literature available.
...