The extreme arrogance of anti-aging medicine

  title={The extreme arrogance of anti-aging medicine},
  author={Robin Holliday},
  • R. Holliday
  • Published 1 April 2009
  • Medicine
  • Biogerontology
The anti-aging medicine movement proposes to alter the human body in order to achieve extreme longevity. To do this it has to reverse or by-pass the multiple causes of human aging. These include a large number of age-associated pathologies, each of which is being studied in great detail in research laboratories around the world. The protagonists of anti-aging medicine claim that it will be far more successful than the combined efforts of the innumerable scientists carrying out this research… 

Molecular gerontology: from homeodynamics to hormesis.

  • S. Rattan
  • Medicine
    Current pharmaceutical design
  • 2014
A promising strategy in biogerontology is to slow down aging and to extend healthspan by hormetin-mediated hormesis, which is potentially effective aging modulators.

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This review covers anti-aging strategies involving supplementation of dietary antioxidants such as polyphenols, vitamins E and C, lipoic acid, acetyl carnitine, carnosine and cysteine along with the application of mammalian target of rapamycin inhibitors and plasma membrane redox system activators.

The scientific quest for lasting youth: prospects for curing aging.

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Mechanisms and aging related diseases

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The Scientific Quest for Lasting Youth: Prospects for Curing Aging

The scientific prospect of eradicating human aging is discussed, and it is argued that curing aging is scientifically possible and not even the most challenging enterprise in the biosciences.

In Search of Immortality: The Political Economy of Anti-aging Medicine

Anti-aging medicine is characterised by significant ‘hype’, hope and promise. This article examines the conditions giving rise to and sustaining this field. It questions its key premises, highlights

From gerontology to geroscience: a synopsis on ageing

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Progress & Prospects: Gene therapy in aging

Whether genetic redesigning can be achieved in the wake of numerous and complex epigenetic factors that effectively determine the life course and the life span of an individual still appears to be a ‘mission impossible’.



Introduction Anti-Aging Medicine: The Hype and the Reality—Part I

In this issue and the previous issue of the Journal of Gerontology: Biological Sciences, scientists from a broad range of disciplines discuss various topics associated with the hype and reality behind anti-aging medicine.

Anti-Aging Medicine: The Hype and Reality—I

In this and the following issue of the Journal of Gerontology: Biological Sciences, scientists from a broad range of disciplines discuss various topics associated with the hype and reality behind anti-aging medicine.

Position statement on human aging.

52 researchers in the field of aging have collaborated to inform the public of the distinction between the pseudoscientific antiaging industry, and the genuine science of aging that has progressed rapidly in recent years.

New Horizons for the Clinical Specialty of Anti‐aging Medicine: The Future with Biomedical Technologies

  • R. Klatz
  • Medicine, Biology
    Annals of the New York Academy of Sciences
  • 2005
Because it embraces the use of biomedical technology, anti‐aging medicine offers a hopeful model of health care in which healthy human life spans of 120 years and longer may be achieved—if the authors employ anti-aging therapeutics today, and encourage the continued expansion of biomedical technologies to prevent, treat, and cure diseases.

No truth to the fountain of youth.

Alarmed by these trends, scientists who study aging, including the three of us, have issued a position statement containing this warning: no currently marketed anti-aging products are being marketed.

Longevity, senescence, and the genome

By comparing species that have different developmental and life spans, Finch proposes a typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.

Science fact and the SENS agenda

In an article published in the EMBO reports Special Issue on Time and Ageing, Aubrey D.N.J. de Grey criticizes biogerontologists for what he sees as their generally pessimistic view of the

How and why we age

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Extrapolaholics anonymous: why demographers' rejections of a huge rise in cohort life expectancy in this century are overconfident.

Criticisms of demographers by other demographers have become frequent in scientific literature, generally consisting of accusations that trends observed in the recent past have been extrapolated