The extraction, isolation and purification of an endogenous regulator for the 5-HT2 receptor.

  • Jose Apud
  • Published 2011 in Pharmacological research


Early studies indicated that serotonin, a primary transmitter in the central nervous system, may not represent the primary endogenous regulator for the 5-HT2 receptor labeled by [3H]-ketanserin. Instead, an endogenous ligand may be responsible for modulating the [3H]-ketanserin site. Through different isolation and purification procedures, a pronase… (More)
DOI: 10.1016/j.phrs.2011.05.022


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