The extracellular matrix protein TGFBI promotes myofibril bundling and muscle fibre growth in the zebrafish embryo.

@article{Kim2009TheEM,
  title={The extracellular matrix protein TGFBI promotes myofibril bundling and muscle fibre growth in the zebrafish embryo.},
  author={Hyejeong Rosemary Kim and Philip W Ingham},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2009},
  volume={238 1},
  pages={56-65}
}
The extracellular matrix protein Tgfbi has been shown to localise to myotendinous junctions in mouse and postulated to interact with the transmembrane protein Integrin alpha7beta1, which, in parallel with the Dystrophin-associated protein complex, is critical for linkage between the extracellular matrix and the cytoskeleton of muscle fibres. Here we use a GFP-tagged form of Tgfbi to analyse its distribution in the developing skeletal muscle of the zebrafish embryos and antisense morpholino… CONTINUE READING