The extent of fetal ossification as an index of delayed development in teratogenic studies on the rat.

@article{Aliverti1979TheEO,
  title={The extent of fetal ossification as an index of delayed development in teratogenic studies on the rat.},
  author={V. Aliverti and L Bonanomi and Erminio Giavini and Vincenzo Leone and Luigi Mariani},
  journal={Teratology},
  year={1979},
  volume={20 2},
  pages={237-42}
}
In teratogenic studies toxic effects may manifest themselves in retarded fetal development, such as a reduction in fetal weight. In searching for an additional index, the number of centers of ossification in seven skeletal districts (sternum, metacarpus, metatarsus, cervical and caudal vertebrae, anterior and posterior proximal phalanges) of rat fetuses delivered on days 19, 20 and 21 of gestation were counted and compared. Results showed uneven ossification in day-19 and -20 fetuses, but… CONTINUE READING
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