The expression pattern of the Distal-less homeo☐-containing gene Dlx-5 in the developing chick limb bud suggests its involvement in apical ectodermal ridge activity, pattern formation, and cartilage differentiation

@article{Ferrari1995TheEP,
  title={The expression pattern of the Distal-less homeo☐-containing gene Dlx-5 in the developing chick limb bud suggests its involvement in apical ectodermal ridge activity, pattern formation, and cartilage differentiation},
  author={Deborah Ferrari and Lauro Sumoy and Jennifer Gannon and Hailing Sun and Anthony M. C. Brown and William B. Upholt and Robert A. Kosher},
  journal={Mechanisms of Development},
  year={1995},
  volume={52},
  pages={257-264}
}
Here we report the isolation from a chick limb bud cDNA library of a cDNA that contains the full coding sequence of chicken Dlx-5, a member of the Distal-less (Dlx) family of homeobox-containing genes that encode homeodomains highly similar to that of the Drosophila Distal-less gene, a gene that is required for limb development in the Drosophila embryo. The expression pattern of Dlx-5 in the developing chick limb bud suggests that it may be involved in several aspects of limb morphogenesis. Dlx… CONTINUE READING
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