The expression of the p85α subunit of phosphatidylinositol 3-Kinase is induced by activation of the peroxisome proliferator-activated receptor γ in human adipocytes

@article{Rieusset2001TheEO,
  title={The expression of the p85α subunit of phosphatidylinositol 3-Kinase is induced by activation of the peroxisome proliferator-activated receptor γ in human adipocytes},
  author={Jennifer Rieusset and C{\'e}cile Chambrier and Karim Bouzakri and Eric Dusserre and Johan Auwerx and J Riou and Martine Laville and Hubert Vidal},
  journal={Diabetologia},
  year={2001},
  volume={44},
  pages={544-554}
}
Aims/hypothesis. Thiazolidinediones are new oral antidiabetic drugs that activate the nuclear receptor PPARγ. Our aim was to identify potential target genes of PPARγ in the human adipocyte in order to clarify how thiazolidinediones improve insulin sensitivity. Methods. The effect of BRL 49 653 (Rosiglitazone) on the mRNA expression of insulin receptor… CONTINUE READING