The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells.

@article{Jung2003TheEO,
  title={The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells.},
  author={Benjamin Jung and Denis G. M. Jugloff and Guangming Zhang and Richard Martin Logan and Stephanie K. Brown and James H. Eubanks},
  journal={Journal of neurobiology},
  year={2003},
  volume={55 1},
  pages={
          86-96
        }
}
Mutations in the MeCP2 gene cause Rett syndrome, a neurologic condition affecting primarily young girls. To gain insight into the normal function of MeCP2, we examined its temporal and spatial expression patterns, and immunoreactive prevalence, during late embryonic and perinatal brain development. MeCP2 mRNA was detected in most regions of the developing rat brain by the late embryonic stage. Regions displaying the strongest mRNA expression include the hippocampus, cortex, and cerebellum, and… CONTINUE READING
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