The expression of heparanase and microRNA-1258 in human non-small cell lung cancer

@article{Liu2012TheEO,
  title={The expression of heparanase and microRNA-1258 in human non-small cell lung cancer},
  author={Hongcheng Liu and Xiaofeng Chen and Wen Gao and Gening Jiang},
  journal={Tumor Biology},
  year={2012},
  volume={33},
  pages={1327-1334}
}
This study aims to discuss the correlation between miR-1258 and the expression of heparanase (HPSE) in the cancer cells of the patients with non-small cell lung cancer (NSCLC) and the inhibition mechanism of miR-1258 on the invasion of lung cancer cell. The expression level of miR-1258 was detected by TaqMan real-time PCR assay, the expression of HPSE was detected by immunohistochemistry, and the expression level of HPSE in the cancer tissue of each case was detected by western blot and in its… CONTINUE READING
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