The expression of cyclooxygenase-1, cyclooxygenase-2 and 5-lipoxygenase in inflammatory muscle tissue of patients with polymyositis and dermatomyositis.

@article{Studnkov2004TheEO,
  title={The expression of cyclooxygenase-1, cyclooxygenase-2 and 5-lipoxygenase in inflammatory muscle tissue of patients with polymyositis and dermatomyositis.},
  author={J. Tomasov{\'a} Stud{\'y}nkov{\'a} and Stefan Kuchen and Elvira Jeisy and Joerg Schedel and F. Alexander Charvat and Kateřina Jaro{\vs}ov{\'a} and Haiko Sprott and Mohammad Movahedi and Renate E. Gay and Beat Michel and Karel Pavelka and Jiř{\'i} Vencovsk{\'y} and S. Hubertus Gay},
  journal={Clinical and experimental rheumatology},
  year={2004},
  volume={22 4},
  pages={
          395-402
        }
}
OBJECTIVE To describe cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) expression in muscle tissue in patients with idiopathic inflammatory myopathies (IIM) - dermatomyositis (DM) and polymyositis (PM) and to find out if any differences between affected and non-affected muscles detected by MRI exist. METHODS Samples of muscle tissue from 7 patients with dermatomyositis (DM) and from 4 with polymyositis (PM) were obtained by needle biopsy from affected and non… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

Why there are two cyclooxygenase isozymes.

  • The Journal of clinical investigation
  • 2001
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Pathogenesis of idiopathic inflammatory myopathies. I n W O RT M A N N R L (Ed.): Diseases of Skeletal Muscle

R PMESSNER
  • 2000
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Cyclooxygenase in biology and disease.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 1998
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Cyclooxy - genase - 1 and - 2 are expressed by human T cells

JL PABLOS, B SANTIAGO, E CARREIRAP, M GALINDO, JJ GOMEZ-REINO
  • Clin Exp Immunol
  • 2003