The expression of MMP-8 in human odontoblasts and dental pulp cells is down-regulated by TGF-beta1.

@article{Palosaari2000TheEO,
  title={The expression of MMP-8 in human odontoblasts and dental pulp cells is down-regulated by TGF-beta1.},
  author={Heidi Palosaari and Jaana Wahlgren and Markku Larmas and H R{\"o}nk{\"a} and Timo Sorsa and Tuula Salo and Leo Tj{\"a}derhane},
  journal={Journal of dental research},
  year={2000},
  volume={79 1},
  pages={77-84}
}
Recent findings show that matrix metalloproteinase-8 (MMP-8) is expressed, in addition to neutrophils, by human chondrocytes, cultured fibroblasts, and endothelial cells. We investigated the expression of MMP-8 in other human mesenchyme-derived cells, odontoblasts, and pulp tissue. Odontoblasts and pulp tissue were collected from extracted human teeth for MMP-8 mRNA analysis with reverse-transcription/polymerase chain-reaction (RT-PCR) and Southern blot. The expression, localization, and… CONTINUE READING
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