The expression of Ep-CAM (17-1A) in squamous cell cancers of the lung.

  title={The expression of Ep-CAM (17-1A) in squamous cell cancers of the lung.},
  author={Chandrika J. Piyathilake and Andra R. Frost and Heidi Weiss and Upender Manne and Douglas Corbett Heimburger and William E. Grizzle},
  journal={Human pathology},
  volume={31 4},
Immunotherapy trials using monoclonal antibodies 323/A3 and 17-1A that recognize Ep-CAM, including trials focused on cancer of the lung, currently are underway. Nevertheless, there have been few comprehensive evaluations of the expression of Ep-CAM in specific types of neoplastic processes, including cancer of the lung. The current study of 60 human subjects with squamous cell cancer (SCC) of the lung, selected at random, was undertaken (1) to examine the expression of Ep-CAM in SCC and… CONTINUE READING


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