The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: role in formation of metastasis.

@article{Czyewska2010TheEO,
  title={The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: role in formation of metastasis.},
  author={Jolanta Czyżewska and katarzyna Guzińska-ustyMowiCz and Marek Ustymowicz and Anna Pryczynicz and Andrzej Kemona},
  journal={Folia histochemica et cytobiologica},
  year={2010},
  volume={48 1},
  pages={37-45}
}
The E-cadherin-catenin complex plays an important role in the process of cell adhesion. Its dysfunction is associated with a decrease in cell differentiation and with increased invasiveness and metastasis. Our aim was to evaluate the expression of E-cadherin and B-catenin in advanced gastric cancer in relation to selected clinico-pathomorphological parameters. Formalin-fixed, paraffin-embedded tissue specimens were immunohistochemically stained with monoclonal antibodies E-cadherin (NCL-E-Cad… CONTINUE READING

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