The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.

Abstract

Numerous chemicals increase the metabolic capability of organisms by their ability to activate genes encoding various xenochemical-metabolizing enzymes, such as cytochromes P450 (CYPs), transferases and transporters. For example, natural and synthetic glucocorticoids (agonists and antagonists) as well as other clinically important drugs induce the hepatic… (More)

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Cite this paper

@article{Pascussi2003TheEO, title={The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.}, author={Jean Marc Pascussi and Sabine Gerbal-chaloin and Lionel Drocourt and Patrice Maurel and Marie Jos{\'e} Vilarem}, journal={Biochimica et biophysica acta}, year={2003}, volume={1619 3}, pages={243-53} }