The expression of CD146 predicts a poor overall survival in patients with adenocarcinoma of the lung.

  title={The expression of CD146 predicts a poor overall survival in patients with adenocarcinoma of the lung.},
  author={Soichi Oka and Hidetaka Uramoto and Yasuhiro Chikaishi and Fumihiro Tanaka},
  journal={Anticancer research},
  volume={32 3},
BACKGROUND The epithelial-mesenchymal transition (EMT) is also involved in cancer progression and metastasis. The expression of mesenchymal marker genes might be associated with a more aggressive form of the disease. CD146 is a marker of mesenchymal cells, a potentially metastasis-promoting cell adhesion molecule, and its expression has been described in various types of solid tumors. We, herein, evaluated the expression of CD146 in patients with adenocarcinoma of the lung by using… CONTINUE READING

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