The expression and function of cadherin-mediated cell-to-cell adhesion in human embryonal carcinoma cells

@article{Giesberts1999TheEA,
  title={The expression and function of cadherin-mediated cell-to-cell adhesion in human embryonal carcinoma cells},
  author={Aukje N. Giesberts and Cristina Duran and Ian N Morton and Christine Pigott and Stanley J White and Peter W. Andrews},
  journal={Mechanisms of Development},
  year={1999},
  volume={83},
  pages={115-125}
}

Figures from this paper

Dickkopf‐3 alters the morphological response to retinoic acid during neuronal differentiation of human embryonal carcinoma cells
TLDR
Findings suggest that Dkk‐3 plays a role in the regulation of cell interactions during RA‐induced neuronal differentiation.
High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation
TLDR
It is shown that miR-363 contributes to pluripotency maintenance, at least in part, by targeting NOTCH1 and PSEN1 and inhibiting Notch-induced differentiation, a mechanism that could be implicated in naïve and primed pluripotent states.
Arrayed functional genetic screenings in pluripotency reprogramming and differentiation
TLDR
All studies carried up to date that used arrayed screening approaches to explore the function of these genetic elements on those biological contexts, using focused or genome-wide genetic libraries are reviewed.
Origin, Migration, and Proliferation of Human Primordial Germ Cells
TLDR
This chapter describes the life history of human PGCs combining old and new information and, where appropriate, making use of the most recent results obtained in the mouse.
Identification and characterization of regulators of survival in human pluripotent stem cells
TLDR
This work confirmed that inhibiting ROCK activity in hPSCs improves their survival by inhibiting dissociation-induced apoptosis, and identified several novel small molecules that most function through inhibition of ROCK, suggesting that ROCK activity is a key modulator of survival in h PSCs.
Cell‐Cell Signaling Through NOTCH Regulates Human Embryonic Stem Cell Proliferation
TLDR
The results indicate that cell‐cell signaling through the NOTCH system provides a critical cue for the proliferation of human EC and ES cell in vitro.
Pleiotrophin Enhances Clonal Growth and Long‐Term Expansion of Human Embryonic Stem Cells
TLDR
Findings reveal the underlying importance of PTN in hESC survival and its usefulness in the clonal manipulation and large‐scale propagation of hESCs.
...
1
2
...

References

SHOWING 1-10 OF 58 REFERENCES
Activation of the Wnt signaling pathway: a molecular mechanism for lithium action.
TLDR
It is shown that lithium inhibits GSK-3 beta from species as diverse as Dictyostelium discoideum and Xenopus laevis, providing a biochemical mechanism for the action of lithium on the development of these organisms.
A molecular mechanism for the effect of lithium on development.
  • P. S. Klein, D. Melton
  • Biology, Psychology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1996
TLDR
It is shown that complete inhibition of IMPase has no effect on the morphogenesis of Xenopus embryos and a different hypothesis to explain the broad action of lithium is presented, which suggests that lithium acts through inhibition of glycogen synthase kinase-3 beta (GSK-3beta), which regulates cell fate determination in diverse organisms including Dictyostelium, Drosophila, and Xenopus.
Comparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours
The pattern of cell surface antigen expression of a set of cell lines derived from human germ cell tumours and corresponding to various cell phenotypes found within these tumours was studied using
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.
TLDR
It is demonstrated thatosphorylation of beta-catenin in vivo requires an in vitro amino-terminal Xgsk-3 phosphorylation site, which is conserved in the Drosophila protein armadillo, which provides a basis for understanding the interaction between XgSk-3 and beta-catsin in the establishment of the dorsal-ventral axis in early Xenopus embryos.
Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes.
TLDR
The Wnt-1 signal transduction pathway leads to the accumulation of monomeric catenins and stabilization of catenin complex formation with both APC and cadherins.
Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
TLDR
Results indicate that GSK-3 is required for ventral differentiation, and suggest that dorsal differentiation may involve the suppression of G SK-3 activity by a wingless/wnt-related signal.
Germ lines from human germ-cell tumours Atlas of human tumor cell lines, Academic press
  • Germ lines from human germ-cell tumours Atlas of human tumor cell lines, Academic press
  • 1994
...
1
2
3
4
5
...