The expression and function of cadherin-mediated cell-to-cell adhesion in human embryonal carcinoma cells
@article{Giesberts1999TheEA, title={The expression and function of cadherin-mediated cell-to-cell adhesion in human embryonal carcinoma cells}, author={Aukje N. Giesberts and Cristina Duran and Ian N Morton and Christine Pigott and Stanley J White and Peter W. Andrews}, journal={Mechanisms of Development}, year={1999}, volume={83}, pages={115-125} }
15 Citations
Dickkopf‐3 alters the morphological response to retinoic acid during neuronal differentiation of human embryonal carcinoma cells
- BiologyDevelopmental neurobiology
- 2014
Findings suggest that Dkk‐3 plays a role in the regulation of cell interactions during RA‐induced neuronal differentiation.
High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation
- BiologyStem cell research & therapy
- 2019
It is shown that miR-363 contributes to pluripotency maintenance, at least in part, by targeting NOTCH1 and PSEN1 and inhibiting Notch-induced differentiation, a mechanism that could be implicated in naïve and primed pluripotent states.
Arrayed functional genetic screenings in pluripotency reprogramming and differentiation
- BiologyStem Cell Research & Therapy
- 2018
All studies carried up to date that used arrayed screening approaches to explore the function of these genetic elements on those biological contexts, using focused or genome-wide genetic libraries are reviewed.
Origin, Migration, and Proliferation of Human Primordial Germ Cells
- Biology
- 2013
This chapter describes the life history of human PGCs combining old and new information and, where appropriate, making use of the most recent results obtained in the mouse.
Identification and characterization of regulators of survival in human pluripotent stem cells
- Biology
- 2012
This work confirmed that inhibiting ROCK activity in hPSCs improves their survival by inhibiting dissociation-induced apoptosis, and identified several novel small molecules that most function through inhibition of ROCK, suggesting that ROCK activity is a key modulator of survival in h PSCs.
Retinoic acid directs neuronal differentiation of human pluripotent stem cell lines in a non-cell-autonomous manner.
- BiologyDifferentiation; research in biological diversity
- 2010
Cell‐Cell Signaling Through NOTCH Regulates Human Embryonic Stem Cell Proliferation
- BiologyStem cells
- 2008
The results indicate that cell‐cell signaling through the NOTCH system provides a critical cue for the proliferation of human EC and ES cell in vitro.
Pleiotrophin Enhances Clonal Growth and Long‐Term Expansion of Human Embryonic Stem Cells
- BiologyStem cells
- 2007
Findings reveal the underlying importance of PTN in hESC survival and its usefulness in the clonal manipulation and large‐scale propagation of hESCs.
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