The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment.

Abstract

While no single model can exactly recapitulate all aspects of multiple sclerosis (MS), animal models are essential in understanding the induction and pathogenesis of the disease and to develop therapeutic strategies that limit disease progression and eventually lead to effective treatments for the human disease. Several different models of MS exist, but by… (More)
DOI: 10.1016/B978-0-444-52001-2.00008-X

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Cite this paper

@article{Robinson2014TheEA, title={The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment.}, author={Andrew P. Robinson and Christopher T Harp and Avertano Noronha and Stephen D. Miller}, journal={Handbook of clinical neurology}, year={2014}, volume={122}, pages={173-89} }