The expanding superfamily of gelsolin homology domain proteins

@article{Ghoshdastider2013TheES,
  title={The expanding superfamily of gelsolin homology domain proteins},
  author={Umesh Ghoshdastider and David Popp and Leslie D. Burtnick and Robert Charles Robinson},
  journal={Cytoskeleton},
  year={2013},
  volume={70}
}
The gelsolin homology (GH) domain has been found to date exclusively in actin‐binding proteins. In humans, three copies of the domain are present in CapG, five copies in supervillin, and six copies each in adseverin, gelsolin, flightless I and the villins: villin, advillin and villin‐like protein. Caenorhabditis elegans contains a four‐GH‐domain protein, GSNL‐1. These architectures are predicted to have arisen from gene triplication followed by gene duplication to result in the six‐domain… 
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TLDR
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