The expanding role of fluoroquinolones.

  title={The expanding role of fluoroquinolones.},
  author={Anthony Schaeffer},
  journal={Disease-a-month : DM},
  volume={49 2},
There has been a growing rate of resistance among common urinary tract pathogens, such as Escherichia coli, to traditional antimicrobial therapies including the "gold standard" trimethoprim-sulfamethoxazole (TMP-SMX). Consequently, fluoroquinolone antimicrobial agents have taken on an expanding management role for UTIs. In fact, the recent Infectious Diseases Society of America clinical management guidelines for UTI recommend fluoroquinolones as first-line therapy for uncomplicated UTI in areas… CONTINUE READING