The expanding role of Wnt signaling in bone metabolism.

@article{Robling2013TheER,
  title={The expanding role of Wnt signaling in bone metabolism.},
  author={Alexander G. Robling},
  journal={Bone},
  year={2013},
  volume={55 1},
  pages={
          256-7
        }
}
The quest for targetable molecules and pathways that can be manipulated to treat skeletal disease and restore bone health is perpetually evolving. Successful pharmacologic treatment of nearly all skeletal diseases among adults, and many pediatric skeletal diseases, requires a fundamental understanding of the influence that different signaling pathways exert on the bone remodeling cycle. Because pharmacologic agents that improve bone mass and fracture susceptibility can work by increasing [1] or… CONTINUE READING

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