The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds.

Abstract

The process of host cell invasion by Trypanosoma cruzi shares mechanistic elements with plasma membrane injury and repair. Both processes require Ca(2+)-triggered exocytosis of lysosomes, exocytosis of acid sphingomyelinase and formation of ceramide-enriched endocytic compartments. T. cruzi invades at peripheral sites, suggesting a need for spatial… (More)
DOI: 10.1242/jcs.150573

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Cite this paper

@article{Fernandes2015TheEI, title={The exocyst is required for trypanosome invasion and the repair of mechanical plasma membrane wounds.}, author={Maria Cec{\'i}lia Di Ciero Fernandes and Matthias Corrotte and Danilo Ciccone Miguel and Christina Tam and Norma Windsor Andrews}, journal={Journal of cell science}, year={2015}, volume={128 1}, pages={27-32} }