The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum.

@article{Eccles1966TheES,
  title={The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum.},
  author={John Eccles and Rodolfo Llin{\'a}s and Kazunari Sasaki},
  journal={The Journal of physiology},
  year={1966},
  volume={182 2},
  pages={268-96}
}
1. A single climbing fibre makes an extraordinarily extensive synaptic contact with the dendrites of a Purkinje cell. Investigation of this synaptic mechanism in the cerebellum of the cat has been based on the discovery by Szentagothai & Rajkovits (1959) that the climbing fibres have their cells of origin in the contralateral inferior olive.2. Stimulation in the accessory olive selectively excites fibres that have a powerful synaptic excitatory action on Purkinje cells in the contralateral… CONTINUE READING
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