The excitatory effect of ethanol: absence in rats, no tolerance and increased sensitivity in mice.

@article{Masur1986TheEE,
  title={The excitatory effect of ethanol: absence in rats, no tolerance and increased sensitivity in mice.},
  author={Jandira Masur and M L Oliveira de Souza and Asteroides P. Zwicker},
  journal={Pharmacology, biochemistry, and behavior},
  year={1986},
  volume={24 5},
  pages={1225-8}
}
Three questions related to ethanol's stimulating effect (ESE) were studied. The first referred to the reported absence of tolerance to ESE in mice. It was determined whether tolerance would develop if the period of ethanol treatment were extended significantly beyond those normally found in the literature. No evidence of tolerance to ESE was found over a 5-month period of treatment. The second issue related to the possibility that mice not only do not develop tolerance but actually become more… CONTINUE READING

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