The ex vivo chemosensitivity profile of choroidal melanoma.

  title={The ex vivo chemosensitivity profile of choroidal melanoma.},
  author={Nyree E Myatt and Ian A Cree and Christian Martin Kurbacher and Alexander J. E. Foss and John L. Hungerford and Piers Nicholas Plowman},
  journal={Anti-cancer drugs},
  volume={8 8},
Uveal melanoma has a high mortality rate and responds poorly to existing chemotherapy. We have therefore examined the sensitivity of uveal melanoma to cytotoxic agents using an ex vivo chemosensitivity assay to determine whether some agents which have not been used for this tumor might have activity. An ATP-based tumor chemosensitivity assay (ATP-TCA) was used to determine the effect of nine cytotoxic drugs at multiple dilutions in 28 primary uveal melanoma specimens. Evaluable assay results… CONTINUE READING
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Chemosensitivity Testing in Oncology

Recent Results in Cancer Research • 2003
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