The evolving story of the omega subunit of bacterial RNA polymerase.

  title={The evolving story of the omega subunit of bacterial RNA polymerase.},
  author={Renjith Mathew and Dipankar Chatterji},
  journal={Trends in microbiology},
  volume={14 10},
Omega (omega) is the smallest subunit of bacterial RNA polymerase (RNAP). Although identified early in RNAP research, its function remained ambiguous and shrouded by controversy for a considerable period. It has subsequently been shown that the protein has a structural role in maintenance of the conformation of the largest subunit, beta', and recruitment of beta' to the enzyme assembly. Conservation of this function across all forms of life indicates the importance of its role. Several recent… CONTINUE READING

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