The evolving role of catumaxomab in gastric cancer

@article{Lordick2008TheER,
  title={The evolving role of catumaxomab in gastric cancer},
  author={Florian Lordick and Katja Ott and J{\"u}rgen Weitz and Dirk J{\"a}ger},
  journal={Expert Opinion on Biological Therapy},
  year={2008},
  volume={8},
  pages={1407 - 1415}
}
Background: Gastric cancer is a condition with a high medical need. Even after R0 resection the rate of peritoneal and other distant site recurrences is high. Novel therapeutic approaches include trifunctional antibodies (trAb) that recruit and activate different types of immune effector cells at the tumour site. The trAb catumaxomab has dual antigen specificity for epithelial cell adhesion molecule and CD3 and binds to Fcγ-receptor-positive accessory cells. Intraperitoneal administration of… Expand
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