The evolving biology of small molecules: controlling cell fate and identity.

  title={The evolving biology of small molecules: controlling cell fate and identity.},
  author={Jem A. Efe and Sheng Ding},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  volume={366 1575},
Small molecules have been playing important roles in elucidating basic biology and treatment of a vast number of diseases for nearly a century, making their use in the field of stem cell biology a comparatively recent phenomenon. Nonetheless, the power of biology-oriented chemical design and synthesis, coupled with significant advances in screening technology, has enabled the discovery of a growing number of small molecules that have improved our understanding of stem cell biology and allowed… CONTINUE READING
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