The evolutionary transition from RNA to DNA in early cells

@article{Lazcano2005TheET,
  title={The evolutionary transition from RNA to DNA in early cells},
  author={A. Lazcano and R. Guerrero and L. Margulis and J. Or{\'o}},
  journal={Journal of Molecular Evolution},
  year={2005},
  volume={27},
  pages={283-290}
}
  • A. Lazcano, R. Guerrero, +1 author J. Oró
  • Published 2005
  • Biology, Medicine
  • Journal of Molecular Evolution
  • SummaryThe evolution of genetic material can be divided into at least three major phases: first, genomes of “nucleic acid-like” molecules; secondly, genomes of RNA; and finally, double-stranded DNA genomes such as those present in all contemporary cells. Using properties of nucleic acid molecules, we attempt to explain the evolutionary transition from RNA alone as a cellular informational macromolecule prior to the evolution of cell systems based on double-stranded DNA. The idea that… CONTINUE READING
    74 Citations
    Three RNA cells for ribosomal lineages and three DNA viruses to replicate their genomes: a hypothesis for the origin of cellular domain.
    • P. Forterre
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2006
    • 211
    • PDF
    The Evolution of DNA and the Genetic Code
    RNA in evolution
    • N. Lehman
    • Biology, Medicine
    • Wiley interdisciplinary reviews. RNA
    • 2010
    • 22
    The roads to and from the RNA world.
    • 108
    • PDF
    Direct Prebiotic Pathway to DNA Nucleosides.
    • 18
    On the early evolution of RNA polymerase
    • 26
    The Case for an Early Biological Origin of DNA
    • 13
    • PDF
    Viroids: survivors from the RNA world?
    • 93
    • PDF

    References

    SHOWING 1-10 OF 118 REFERENCES
    On the early evolution of RNA polymerase
    • 26
    Evidence for the reductive pathway of deoxyribonucleotide synthesis in an archaebacterium
    • 18
    A minimal living system and the origin of a protocell.
    • J. Oró, A. Lazcano
    • Chemistry, Medicine
    • Advances in space research : the official journal of the Committee on Space Research
    • 1984
    • 25
    The case for an ancestral genetic system involving simple analogues of the nucleotides.
    • 318
    • PDF
    On the fidelity of transcription by Escherichia coli ribonucleic acid polymerase.
    • 66
    Excision repair of uracil during replication of phiX174 DNA in vitro.
    • 4
    Uracil incorporation: a source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome.
    • 115
    • PDF