The evolutionary origin of cardiac chambers.

@article{SimesCosta2005TheEO,
  title={The evolutionary origin of cardiac chambers.},
  author={Marcos S. Sim{\~o}es-Costa and Michelle Almeida Vasconcelos and Allysson Coelho Sampaio and Roberta Mascioli Cravo and Vania L F Linhares and Tatiana Hochgreb and Chao Yun Irene Yan and Brad Davidson and Jos{\'e} Xavier-Neto},
  journal={Developmental biology},
  year={2005},
  volume={277 1},
  pages={
          1-15
        }
}
Identification of cardiac mechanisms of retinoic acid (RA) signaling, description of homologous genetic circuits in Ciona intestinalis and consolidation of views on the secondary heart field have fundamental, but still unrecognized implications for vertebrate heart evolution. Utilizing concepts from evolution, development, zoology, and circulatory physiology, we evaluate the strengths of animal models and scenarios for the origin of vertebrate hearts. Analyzing chordates, lower and higher… CONTINUE READING
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