The evolutionary history of the CD209 (DC-SIGN) family in humans and non-human primates


The CD209 gene family that encodes C-type lectins in primates includes CD209 (DC-SIGN), CD209L (L-SIGN) and CD209L2. Understanding the evolution of these genes can help understand the duplication events generating this family, the process leading to the repeated neck region and identify protein domains under selective pressure. We compiled sequences from 14… (More)
DOI: 10.1038/gene.2008.40


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