The evolutionary dynamics of alpha-satellite.

  title={The evolutionary dynamics of alpha-satellite.},
  author={M Katharine Rudd and Gregory A. Wray and Huntington F. Willard},
  journal={Genome research},
  volume={16 1},
Alpha-satellite is a family of tandemly repeated sequences found at all normal human centromeres. In addition to its significance for understanding centromere function, alpha-satellite is also a model for concerted evolution, as alpha-satellite repeats are more similar within a species than between species. There are two types of alpha-satellite in the human genome; while both are made up of approximately 171-bp monomers, they can be distinguished by whether monomers are arranged in extremely… CONTINUE READING