The evolutionary divergence of Shiga toxin-producing Escherichia coli is reflected in clustered regularly interspaced short palindromic repeat (CRISPR) spacer composition.

@article{Yin2013TheED,
  title={The evolutionary divergence of Shiga toxin-producing Escherichia coli is reflected in clustered regularly interspaced short palindromic repeat (CRISPR) spacer composition.},
  author={Shuang Yin and Mark A. Jensen and Jiawei Bai and Chitrita DebRoy and Rodolphe Barrangou and Edward G Dudley},
  journal={Applied and environmental microbiology},
  year={2013},
  volume={79 18},
  pages={5710-20}
}
The Shiga toxin-producing Escherichia coli (STEC) strains, including those of O157:H7 and the "big six" serogroups (i.e., serogroups O26, O45, O103, O111, O121, and O145), are a group of pathogens designated food adulterants in the United States. The relatively conserved nature of clustered regularly interspaced short palindromic repeats (CRISPRs) in phylogenetically related E. coli strains makes them potential subtyping markers for STEC detection, and a quantitative PCR (qPCR)-based assay was… CONTINUE READING

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CRISPRs in Shiga Toxin-Producing Escherichia coli September 2013 Volume 79 Number 18 aem.asm.org 5719 on M arch 26

  • N Hoe, K Nakashima, +4 authors M Garcia
  • Emerg. Infect. Dis
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