The evolutionary biology of spontaneous abortion in humans.

@article{Forbes1997TheEB,
  title={The evolutionary biology of spontaneous abortion in humans.},
  author={L. Scott Forbes},
  journal={Trends in ecology & evolution},
  year={1997},
  volume={12 11},
  pages={446-50}
}
Human mothers an efficient screening system to eliminate genetically abnormal embryos. However, the incidence of certain birth defects - most notably Down's syndrome - rises with maternal age. Conventional eplanations have focused on a rising production of defective zygotes; in contrast, an evolutionary approach suggest a relaxed maternal screen. Relaxed screening potentially explains the rising incidenee of chromosomal abnormalities in live-births, the incidence of normal embryos in… CONTINUE READING

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