• Corpus ID: 26135793

The evolutionary advantage of recombination. II. Individual selection for recombination.

  title={The evolutionary advantage of recombination. II. Individual selection for recombination.},
  author={Joseph Felsenstein and Shozo Yokoyama},
  volume={83 4},
Based on the FISHER-MULLER theory of the evolution of recombination, an argument can be constructed predicting that a recessive allele favoring recombination will be favored, if there are either favorable or deleterious mutants occurring at other loci. In this case there is no clear distinction between individual and group selection. Computer simulation of populations segregating for recessive or dominant recombination alleles showed selection favoring recombination, except in the case of a… 

Tables and Topics from this paper

Some Advantages and Disadvantages of Recombination
Whether or not the adaptation of a population to an environment is more rapid in the presence of recombination, that is, whether or not recombination speeds up the evolutionary process, depends critically on the ways in which this process is modelled.
The evolution of recombination: removing the limits to natural selection.
It is concluded that selection for recombination will be substantial only if there is tight linkage within the genome or if many loci are subject to directional selection as during periods of rapid evolutionary change.
Population genetic perspectives on the evolution of recombination.
The results from modifier models indicate that decreased recombination rates are usually favored when the population is initially near a polymorphic equilibrium with linkage disequilibrium, and increased recombination may be favored under certain conditions, provided that there is negative epistasis among alleles.
The Hill–Robertson Effect and the Evolution of Recombination
It is shown that recombination is selected through two different effects: it increases the fixation probability of new alleles, and it accelerates selective sweeps, the relative importance of these two effects depends on the relative times of occurrence of the beneficial alleles.
Interference among deleterious mutations favours sex and recombination in finite populations
This work shows that background selection against deleterious mutant alleles provides a stochastic advantage to sex and recombination that increases with population size, and offers a robust and broadly applicable explanation for the evolutionary advantage of recombination.
The evolution of recombination in a heterogeneous environment.
This article examines the joint effects of spatial heterogeneity in selection and epistasis on the evolution of recombination in a model with two patches and finds that including spatial heterogeneity extends the range of epistasis over which recombination can be favored.
Selfish genes, pleiotropy and the origin of recombination.
  • J. Hey
  • Biology, Medicine
  • 1998
The results suggest that a simple model of recombination modifiers, including both neutral and pleiotropic modifiers, is a necessary explanation for the evolutionary origin of recombinations.
Recombination dynamics and the fitness landscape
It is shown that the evolution of recombination depends on the initial frequencies at the selected loci, on the exact shape of selection and on the strength of the selection.
Evolution of recombination in populations experiencing frequency-dependent selection with time delay
  • V. Hutson, R. Law
  • Biology
    Proceedings of the Royal Society of London. Series B. Biological Sciences
  • 1981
Analysis of the model shows that a modifier mutant causing recombination usually starts to spread into a population without recombination, and under certain conditions can spread even if there is already some recombination in the population.
Selective interference among deleterious mutations favours sex and recombination in finite populations regardless of the nature of epistasis
2 Sex and recombination are widespread, but explaining these phenomena has been one of the most difficult problems in evolutionary biology. Recombination is advantageous when different individuals in


Recombination modification in a fluctuating environment
The theory of the evolution of increased recombination between two loci subjected to interactive selection in a temporally fluctuating environment is examined and it seems that the rate of modification of recombination values by this process will be low except when the modifiers are tightly linked to the selected loci.
The effect of genetic linkage on the mean fitness of a population.
  • R. Lewontin
  • Biology, Medicine
    Proceedings of the National Academy of Sciences of the United States of America
  • 1971
It is shown that if the equilibrium vector of gametic frequencies is a continuous function of the set of recombination frequencies among genes, then the mean fitness of the population at equilibrium is a maximum in the absence of recombinations.
The hitch-hiking effect of a favourable gene.
If the selective coefficients at the linked locus are small compared to those at the substituted locus, it is shown that the probability of complete fixation at thelinked locus is approximately exp (— Nc), where c is the recombinant fraction and N the population size.
Towards a theory of the evolution of modifier genes.
A wide variety of random mating systems are subject to selection with modifiers operating, in different cases, on mutation rates, migration between subpopulations, and linkage between other loci, where modifier frequencies evolve in such a way as to maximize the mean fitness of the population at equilibrium.
What use is sex?
  • J. M. Smith
  • Biology, Medicine
    Journal of theoretical biology
  • 1971
It is suggested that the most important advantage of sex arises when two genetically different populations migrate into a new environment, in which the best adapted genotype is a combination of genes from the two invading populations.
The Interrelations of Inversions, Heterosis and Recombination
In individuals heterozygous for an inversion no effective crossing over occurs unless the inversion is, genetically speaking, a very long one, which is, of course, rare in any but long inversions.
Why reproduce sexually?
Abstract There is reason to believe that intense selection, such that only a small minority at the top of the fitness distribution has any appreciable chance of survival, can sometimes give sexual
Some Genetic Aspects of Sex
FPROM the genetic point of view it is advantageous to begin by considering sex in the broader sense of sexuality. It is not generally realized that genetics has finally solved the age-old problem of